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Published Papers
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Published Papers

Challenbio flow cytometers are trusted by leading research institutions across the globe to generate publication-quality data in the most demanding applications. To date, our instruments—including the LongCyte™, FongCyte™, and MateCyte™ platforms—have been cited in over 20 peer-reviewed publications in top-tier journals such as Nature Medicine, with impact factors reaching up to 50.

 

These publications span diverse fields including immunology, oncology, stem cell therapy, nanomedicine, biomaterials engineering, and drug delivery systems, contributed by researchers from global institutions.

 

When you choose Challenbio, you choose a platform proven to support world-class science.

Journal Publication Date Title Field Cited Instrumen Link
Frontiers in Neurology 2024/1/31 Study on the correlation between IL-12p70, IL-17A and migraine in children Neuroscience MateCyte View Paper
Macromolecular Bioscience 2024/1/23 Imidazolium-Based Main-Chain Copolymers With Alternating Sequences for Broad-Spectrum Bactericidal Activity and Eradication of Bacterial Biofilms Biomedical
Engineering,
Biomaterials		 FongCyte View Paper
Biomolecules 2023/11/25 Synthesis and Biological Evaluation of Benzo [4,5]- and Naphtho[2′,1′:4,5]imidazo[1,2-c]pyrimidinone Derivatives Biochemistry,
Immunology,
Molecular Biology		 Longcyte View Paper
Frontiers in Immunology 2024/10/16 Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma Immunology fongcyte View Paper
Stem Cell Research & Therapy 2024/4/1 Safety and efcacy of umbilical cord tissue-derived mesenchymal stem cells
in the treatment of patients with aging frailty: a phase I/II randomized, double-blind,
placebo-controlled study		 Stem Cells Longcyte View Paper
International Journal of Biological Macromolecules 2024/4/25 Quaternary ammonium carboxymethyl chitosan composite hydrogel with efficient antibacterial and antioxidant properties for promoting wound healing Biophysics and
Biochemistry,
Biomedical
Engineering		 Longcyte View Paper
ACS Applied Materials & Interfaces 2024/9/20 Functional Ginger-Derived Extracellular Vesicles-Coated ZIF‑8 Containing TNF‑α siRNA for Ulcerative Colitis Therapy by Modulating Gut Microbiota Materials Science
and Engineering		 Fongcyte View Paper
Acta Biomaterialia 2023/10/29 Engineering a biomimetic system for hepatocyte-specific RNAi treatment of non-alcoholic fatty liver disease Biomaterials,
Tissue Engineering,
Regenerative
Medicine		 FongCyte View Paper
Advanced Healthcare Materials 2024/2/26 Unravelling Immune-Inflammatory Responses and Lysosomal Adaptation: Insights from Two-Photon Excited Delayed Fluorescence Imaging Materials Science,
Biomedicine		 Longcyte View Paper
Journal of Nanobiotechnolog 2023/7/22 Self-polymerized platinum (II)-Polydopamine nanomedicines for photo-chemotherapy of bladder Cancer favoring antitumor immune responses Biomedical engineering, nanotechnology, drug delivery systems FongCyte View Paper
nano today 2024/12/15 Engineered cytomembrane nanovesicles trigger in situ storm of engineered extracellular vesicles for cascade tumor penetration and immune microenvironment remodeling Exosomes Longcyte View Paper
Small 2024/1/21 Relieving Macrophage Dysfunction by Inhibiting SREBP2
Activity: A Hypoxic Mesenchymal Stem Cells-Derived
Exosomes Loaded Multifunctional Hydrogel for Accelerated Diabetic Wound Healing		 Nanoscience and Technology Fongcyte View Paper
Chemical Engineering Journal 2024/10/20 Tumor microenvironment-based smart beacon drug delivery system for in
situ visualization of tumor therapy		 Chemical Engineering, Environmental Chemistry Fongcyte View Paper
Biomaterials 2024/1/8 Bioactive mesoporous silica nanoparticle-functionalized titanium implants with controllable antimicrobial peptide release potentiate the regulation of inflammation and osseointegration Biomedical Engineering FongCyte View Paper
Advanced Science 2024/1/9 Hepatic-Accumulated Obeticholic Acid and Atorvastatin Self-Assembled Nanocrystals Potentiate Ameliorative Effects in Treatment of Metabolic-Associated Fatty Liver Disease Materials Science, Medicine FongCyte View Paper
journal of extracellular vesicles 2024/11/23 Fused extracellular vesicles from M macrophages and human umbilical cord mesenchymal stem cells for the targeted regulation of macrophage pyroptosis in periprosthetic osteolysis Exosomes LongCyte View Paper
ACS NANO 2024/7/30 A Two-Pronged Nanostrategy of Iron Metabolism Disruption to Synergize Tumor Therapy by Triggering the
Paraptosis−Apoptosis Hybrid Pathway		 Nanoscience and Technology FongCyte View Paper
Вестник Уральской медицинской академической науки 2024/9/1（received） ВЛИЯНИЕ ЭКСТРАКТА PHLOJODICARPUS SIBIRICUS
НА ИММУННЫЙ СТАТУС МЫШЕЙ ЛИНИИ ICR		 Medicine, Pharmacology, Toxicology Longcyte View Paper
Медицина экстремальных ситуаций 2024/10/3 Субпопуляции моноцитов и натуральных киллеров периферической крови человека в отдаленном периоде хронического облучения Radiation Biology, Extreme Medicine longcyte View Paper
Hepe  HHbie BonpoCbl B OHKONOrNN 2024/ Antitumor Effect In Vivo and the Impact of Alkalization
Using Sodium Bicarbonate on Viability and Metabolism
of CT26 Tumor Cells		 Oncology Longcyte View Paper
BULLETIN OF RSMU 2024/12/27 Impact of tumor on the cell cycle and differentiation of hematopoietic stem cells Immunology Longcyte View Paper
Advanced Science 2025/3/8 Osteosarcoma Cell-Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis Macrophages, Migrasomes, Oncology FongCyte View Paper
ACS Applied Materials & Interfaces 2024/9/12 Cascade Enzymes Confined in DNA Nanoanchors for Antitumor Therapy Nanomaterials, Enzyme Catalysis, Tumor Therapy FongCyte View Paper
European Journal of Medicinal Chemistry 2025/3/25 Design, Synthesis, and Biological Activity Study of 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline Derivatives Against Multidrug Resistance in Eca109/VCR Cells Medicinal Chemistry, Multidrug Resistance, P-glycoprotein Inhibitors longcyte View Paper
eLife 2025/4/4 CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells Immunology, Cellular Homeostasis, Transcriptional Regulation longcyte View Paper
Biosensors 2025/3/2 Recent Developments (After 2020) in Flow Cytometry Worldwide and Within China Flow Cytometry, Biosensors, Single-cell Analysis longcyte
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fongcyte		 View Paper
Journal of Nanobiotechnology 2025/4/17 Lactobacillus acidophilus extracellular vesicles-coated UiO-66-NH2@siRNA nanoparticles for ulcerative colitis targeted gene therapy and gut microbiota modulation Nanobiotechnology, Ulcerative Colitis Treatment, Gene Therapy, Gut Microbiota Regulation FongCyte View Paper
Microbial Cell Factories 2025/1/7 Salmonella Typhimurium derived OMV
nanoparticle displaying mixed heterologous
O-antigens confers immunogenicity
and protection against STEC infections in mice		 Vaccine Development, Bacterial Infection (STEC), Nanoparticle Delivery Systems FongCyte View Paper
Oncohematology \ Оценка экспрессии молекул CD44 и PD-L1
при сокультивировании опухолевых
и гемопоэтических стволовых клеток		 Oncology LongCyte View Paper
Nano Research 2025/4/30 Simultaneously supplementing Wtp53 and degrading Mutp53 using a virus-mimicking mRNA delivery system to restore P53's autonomous anti-cancer function Nanobiotechnology, Oncology, and Molecular Biology FongCyte View Paper
Journal of Drug Delivery Science and Technology 2025/7/15 A dual-strategy nanomicelle based on starvation therapy for enhancing tumor immunogenicity Tumor Therapy, Nanodrug Delivery, Immunotherapy FongCyte View Paper
Advanced Materials 2025/8/2 A Noninvasive and Highly Effective Inhaled Nanovaccine Based on Natural Polysaccharide for Lung Cancer Treatment Nanomedicine, Cancer Immunotherapy, Polysaccharide Materials FongCyte View Paper
Science Advances 2025/4/30 Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis Applied Science and Engineering (Targeted Therapy for Pulmonary Fibrosis, Nanodrug Delivery) FongCyte View Paper
Advanced Materials 2025/4/1 Inhalable Nanovaccine Based on Bioengineered Bacteria‐Derived Membrane Vesicles Against Lung Metastasis Materials Science and Tumor Immunotherapy (Inhalable Bacterial Membrane Vesicle Nanovaccines, Lung Cancer Metastasis Prevention) FongCyte View Paper
Bioactive Materials   Metal fluoride nanoregulators reverse therapeuticresistance via stemness remodeling to triggerpyroptosis for chemoimmunotherapy Materials Science, Biomedical Engineering, Translational Tumor Medicine FongCyte View Paper
Science Advances 2025/11/21 Renal clearable CRISPR nanosensor targeting
mitochondrial DNA mutation for noninvasive
monitoring of tumor progression and metastasis		 Biomedical Engineering, Molecular Biology, Nanomaterials, Precision Tumor Diagnosis FongCyte View Paper
Advanced Materials 2026/3/5 Inhalable Respiratory Driven Penetration of Porous Microsphere-Based Mucosal Vaccine for Long-Term Immune Protection Inhaled Vaccines FongCyte View Paper
Journal of controlled release 2026/5/10 Tunable microgel modulars for temporally coordinated combination therapy Mucosal Vaccines FongCyte View Paper
Theranostics 2026/1/1 Enhancing cancer susceptibility to disulfidptosis by inducing cell cycle arrest and impairing DNA repair Tumor Metabolism and Cell Death FongCyte View Paper
CNS Neuroscience & Therapeutics 2025/10/27 Integrated Multi-Omics Analysis and Cross-Model
Validation Reveal Mitochondrial Signatures in
Alzheimer's Disease		 Alzheimer's Disease\Mitochondria\Multi-omics CytoStellar AX  View Paper
Nature Medicine 2026/4/29 Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial Immunology / Hematology / Autoimmune Diseases / ITP (Immune Thrombocytopenia) FongCyte View Paper